Linda B. Buck ist eine Neurophysiologin, die am 29. Januar 1947 in Seattle, Washington, geboren wurde. Gemeinsam mit Richard Axel erhielt sie 2004 den Nobelpreis für Physiologie oder Medizin für ihre wegweisende Forschung zum Riechsystem. Bucks wissenschaftliche Karriere führte sie von der Harvard Medical School zur University of Washington in Seattle, wo sie seit 2003 als Professorin für Physiologie tätig ist. Zusätzlich ist sie in der Basic Sciences Division am Fred Hutchinson Cancer Research Center engagiert und forscht am Howard Hughes Medical Institute als Professorin für Physiologie und Biophysik. Ein Meilenstein ihrer Forschung war die Entdeckung, wie Menschen und Tiere in der Lage sind, eine Vielzahl von Gerüchen zu erkennen und zu unterscheiden. In Zusammenarbeit mit Richard Axel schuf sie die Basis für die molekulargenetische Erforschung des Geruchssinns. Ihre Arbeit ermöglichte es, die Prozesse der Geruchswahrnehmung, die Umwandlung in Nervenimpulse und die resultierenden emotionalen Reaktionen im Gehirn besser zu verstehen. Bereits als Postdoktorandin bei Axel identifizierte Buck die Gene, die für die Rezeptoren des Geruchssinns verantwortlich sind. Bucks Forschung konzentriert sich auf die Übertragung von Reizen an das Gehirn, insbesondere auf olfaktorische Reize. Sie untersucht die Entstehung und Entwicklung von Geruchsrezeptoren sowie die Verarbeitung von Gerüchen im Gehirn und deren Auswirkungen auf Reaktionen, Gedanken und Verhalten. Ihre Arbeitsgruppe identifizierte eine Genfamilie von etwa 1000 Genen, die mit der Geruchswahrnehmung in Verbindung stehen und für verschiedene Geruchsrezeptoren codieren. Diese Rezeptoren befinden sich in der Riechschleimhaut und sind direkt mit dem Bulbus olfactorius verbunden, dem Gehirnbereich für die Geruchswahrnehmung. Axel und Buck konnten unabhängig voneinander zeigen, dass jedes Neuron nur einen Rezeptortyp anspricht und dass die Rezeptoren in der Riechschleimhaut zufällig verteilt sind, aber im Bulbus olfactorius in derselben Region wahrgenommen werden. Auf diese Weise entsteht im Gehirn eine komplexe Geruchsempfindung. Neben der Erforschung des Geruchssinns widmete sich Buck auch der Erforschung des Alterns und der genetischen Beeinflussung der Lebensspanne am Beispiel des Fadenwurms Caenorhabditis elegans. In den Jahren 2008 und 2010 zog Buck drei wissenschaftliche Arbeiten zurück, nachdem sie und ihre Mitarbeiter die Ergebnisse eines ehemaligen Mitglieds ihrer Arbeitsgruppe nicht reproduzieren konnten, wobei die Nobelpreisverleihung auf anderen Arbeiten basierte. Im Laufe ihrer Karriere wurde Linda Buck mit zahlreichen Preisen und Ehrungen ausgezeichnet, darunter das Sloan Research Fellowship (1992), der Rosenstiel Award (1996) und die Mitgliedschaft in der National Academy of Sciences (2003). Linda B. Buck wurde im Jahr 2004 mit dem Nobelpreis für ihre bahnbrechenden Leistungen in der Wissenschaft geehrt.
Linda Buck’s research has transformed the field of odorant perception through the cloning of mammalian olfactory receptors. Together with Richard Axel, Buck developed an ingenious method to identify a G protein-coupled odorant receptor family of unprecedented size, comprising up to 1000 distinct genes members. Buck then used olfactory receptor genes as molecular tools to gain insight into the mechanisms and organisations strategies underlying odor perception. Her work showed that the olfactory epithelium is comprised of spatial zones that express different sets of receptor genes and that each zone is a mosaic of randomly interspersed neurons expressing different receptors. Buck then showed that individual olfactory neurons express a single receptor gene. In later work, Buck has documented the organization of olfactory axonal projections into the brain.
Buck’s work has been recognised by award of the 2004 Nobel Prize. This file is licensed under the Creative Commons Attribution-Share Alike 3.0 Unported license.Attribution: The Royal Society
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Linda Buck’s research has transformed the field of odorant perception through the cloning of mammalian olfactory receptors. Together with Richard Axel, Buck developed an ingenious method to identify a G protein-coupled odorant receptor family of unprecedented size, comprising up to 1000 distinct genes members. Buck then used olfactory receptor genes as molecular tools to gain insight into the mechanisms and organisations strategies underlying odor perception. Her work showed that the olfactory epithelium is comprised of spatial zones that express different sets of receptor genes and that each zone is a mosaic of randomly interspersed neurons expressing different receptors. Buck then showed that individual olfactory neurons express a single receptor gene. In later work, Buck has documented the organization of olfactory axonal projections into the brain.
Buck’s work has been recognised by award of the 2004 Nobel Prize. This file is licensed under the Creative Commons Attribution-Share Alike 3.0 Unported license.Attribution: The Royal Society
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Linda Buck’s research has transformed the field of odorant perception through the cloning of mammalian olfactory receptors. Together with Richard Axel, Buck developed an ingenious method to identify a G protein-coupled odorant receptor family of unprecedented size, comprising up to 1000 distinct genes members. Buck then used olfactory receptor genes as molecular tools to gain insight into the mechanisms and organisations strategies underlying odor perception. Her work showed that the olfactory epithelium is comprised of spatial zones that express different sets of receptor genes and that each zone is a mosaic of randomly interspersed neurons expressing different receptors. Buck then showed that individual olfactory neurons express a single receptor gene. In later work, Buck has documented the organization of olfactory axonal projections into the brain.
Buck’s work has been recognised by award of the 2004 Nobel Prize. This file is licensed under the Creative Commons Attribution-Share Alike 3.0 Unported license.Attribution: The Royal Society
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share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.https://creativecommons.org/licenses/by-sa/3.0CC BY-SA 3.0 Creative Commons Attribution-Share Alike 3.0 truetrue
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Linda Buck’s research has transformed the field of odorant perception through the cloning of mammalian olfactory receptors. Together with Richard Axel, Buck developed an ingenious method to identify a G protein-coupled odorant receptor family of unprecedented size, comprising up to 1000 distinct genes members. Buck then used olfactory receptor genes as molecular tools to gain insight into the mechanisms and organisations strategies underlying odor perception. Her work showed that the olfactory epithelium is comprised of spatial zones that express different sets of receptor genes and that each zone is a mosaic of randomly interspersed neurons expressing different receptors. Buck then showed that individual olfactory neurons express a single receptor gene. In later work, Buck has documented the organization of olfactory axonal projections into the brain.
Buck’s work has been recognised by award of the 2004 Nobel Prize. This file is licensed under the Creative Commons Attribution-Share Alike 3.0 Unported license.Attribution: The Royal Society
You are free:
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Nobel Laureate Linda Buck (Medicine, 2004) in NYC, on a bus heading to a Golden Plate Award event, cropped from Betsy Devine's original photo which includes Aaron Ciechanover (Chemistry, 2004) in shot
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Bildquelle: Linda-Buck-1993.jpg Autor: Wikipedia / National Institutes of Health (NIH) photo archives. Lizenz: gemeinfrei
Linda Buck, Ph.D. addressing the 5th Anniversary symposium of the National Institute of Deafness and Other Communication Disorders (NIDCD), National Institutes of Health (NIH), Bethesda MD, U.S.A.
Nobel Laureate Linda Buck (Medicine, 2004) in NYC, on a bus heading to a Golden Plate Award event, cropped from Betsy Devine's original photo which includes Aaron Ciechanover (Chemistry, 2004) in shot
Nobel Laureate Linda Buck (Medicine, 2004) in NYC, on a bus heading to a Golden Plate Award event, cropped from Betsy Devine's original photo which includes Aaron Ciechanover (Chemistry, 2004) in shot
Nobel Laureate Linda Buck (Medicine, 2004) in NYC, on a bus heading to a Golden Plate Award event, cropped from Betsy Devine's original photo which includes Aaron Ciechanover (Chemistry, 2004) in shot
President George W. Bush meets with the 2004 Nobel Laureates in the Oval Office. Pictured with President Bush, from left, are Dr. Linda Buck, physiology and medicine; Finn Kydland, economics; Edward Prescott, economics; Frank Wilczek, physics; David Gross, physics; and Richard Axel, physiology and medicine.
Linda B. Buck ist eine 🙋♀️ US-amerikanische Neurophysiologin und Nobelpreis-Trägerin
Wie alt ist Linda B. Buck?
Linda B. Buck ist ⌛ 79 Jahre alt. Bis zu ihrem nächsten Geburtstag am 29. Januar 2027 sind es noch 338 Tage.
Wann hat Linda B. Buck Geburtstag?
Linda B. Buck wurde an einem Mittwoch am ⭐ 29. Januar 1947 geboren.
Wo wurde Linda B. Buck geboren?
Linda B. Buck wurde in 🚩 Seattle, Washington, USA, geboren.
Ist Linda B. Buck verheiratet oder hat sie einen Partner?
Ja, Linda B. Buck ist aktuell verheiratet. Ihr Ehemann ist Roger Brent.
In welchem Sternzeichen wurde Linda B. Buck geboren?
Linda B. Buck wurde im westlichen Sternzeichen Wassermann geboren. Nach der chinesischen Astrologie ist ihr Tierkreiszeichen das Schwein 猪 mit dem Element Feuer ('Feuer-Schwein').
Diese Seite wird auch unter folgenden Suchbegriffen gefunden: Alter Linda B. Buck | Linda B. Buck Steckbrief | Linda B. Buck Größe | Linda B. Buck Geburtstag | Linda B. Buck geboren | Linda B. Buck Geburtsort | Linda B. Buck Alter | Linda B. Buck Geburtsdatum | Linda B. Buck Sternzeichen | In welchem Sternzeichen wurde Linda B. Buck geboren | Wo wurde Linda B. Buck geboren | Alter von Linda B. Buck Du befindest dich auf der Seite Linda B. Buck Einige Textpassagen dieser Seite stammen aus dem Wikipedia-Artikel Linda B. Buck, Lizenz: CC-BY-SA 3.0, Autor/en: Liste.
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